3D Co-culture system
3D Co-culture system

SKOV3 Cells Migration on a Chip
SKOV3 Cells Migration on a Chip

Biomicrofluidics and Material
Biomicrofluidics and Material

3D Co-culture system
3D Co-culture system

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Systems Analysis of Cellular Communication

The FRUITS lab is actively pursuing a highly interdisciplinary and emerging field of lab-on-a-chip, novel microfluidic tools for cell biology. Our current interests are in the development of novel devices to enhance the fundamental knowledge on the cell to cell communication in cancer, molecular interactions of dendritic cells and cancer cells. 
 

Physics of cells and Tissues

- The effects of curvature in cell microenvironments

- Immune cell migration

DCmigration.jpg

References

 

• Acta Biomaterialia, 77, 311-321 (2018)

• Lab Chip 17, 4171-4185 (2017)

• Scientific Reports, 6, 30207 (2016)

• Integrative Biology, 6, 267-276 (2014)

 Tumor Microenvironments

- Single cell level platform

JY_singlecell_1.png
JY_singlecell_2.png

- Co-culture platform

coculture_1.png
coculture_2.png

- 3D spheroid platform

spheroid.png

References

 

•  Scientific Reports, 7, 2050 (2017)

•  Integr. Biol., 6, 267-276 (2014)

•  Biomedical Microdevices, 15, 4, 627-634 (2013)

•  ACS Appl. Mater. Interfaces, 10, 40, 33839-33846 (2018)