[95] ​Submitted

Junyoung Kim, Chaeeun Lee, Inun Kim, Yoohong Min, Vijaya Sunkara, Juhee Park, Yang-Seok Park, Issac. J. Michael, Jooyoung Ro, Yoon-Kyoung Cho*

TGFβ1 in Breast Tumor-Derived Extracellular Vesicles Promotes the Adhesion of Circulating Tumor Cells on 3D Human Liver Chip

[94] Submitted

Yang-Seok Park, Jung Min Oh, Junyoung Kim, Seungyoung Park, Seungse Cho, Hyunhyub Ko, Yoon-Kyoung Cho*

Near-field electrospinning for 3D stacked nanoarchitectures with high aspect ratio

[93] Submitted

Hyera Kim‡, Minji Lim‡, Jin Young Kim, So-Jin Shin, Yoon-Kyoung Cho*, Chi Heum Cho*

Circulating tumor cells enumerated by a centrifugal microfluidic device as a predictive marker for treatment monitoring of ovarian cancer patients

[92] Submitted

Monsur Jiaul Haque, Sumit Kumar, Jonathan Sabaté del Río, and Yoon-Kyoung Cho

Highly Sensitive Detection of Hydrazine on Poly(Tannic Acid)-Coated Disposable Carbon Electrode

[91] ​Submitted

 Dongyoung Kim‡, Hyun-Kyung Woo‡, Chaeeun Lee, Yoohong Min, Hong Koo Ha, and Yoon-Kyoung Cho*

ExoFind: Identifying tumor-specific extracellular vesicles by size fractionation and single-vesicle analysis

[90] Submitted

Dongyoung Kim, Yoohong Min, Jung Min Oh, and Yoon-Kyoung Cho*

AI-powered transmitted light microscopy for functional analysis of live cells

[89]Nature Biomedical Engineering, 2019, accepted

Issac Michael, Dongyoung Kim, Oleksandra Gulenko, Saravana Kumar, Jothi Clara, Sumit Kuma[]r, Dong-Yeob Ki, Juhee Park, Hyun Yong Jeong, Taek Soo Kim, Sunghoon Kwon, and Yoon-Kyoung Cho*

Dx-Fidget Spinner: A Pocket-Sized, Low-Cost, Hand-Powered Centrifuge for Point-of-Care Diagnostics of Infectious Diseases

The possibility of functional roles played by platelets in close alliance with cancer cells has inspired the design of new biomimetic systems that exploit platelet–cancer cell interactions. Here, the role of platelets in cancer diagnostics is leveraged to design a microfluidic platform capable of detecting cancer‐derived extracellular vesicles (EVs) from ultrasmall volumes (1 µL) of human plasma samples. Further, the captured EVs are counted by direct optical coding of plasmonic nanoprobes modified with EV‐specific antibodies. Owing to the diverse function proteins associated with human platelets that can bind to the wide spectrum of cancer cell-derived extracellular vesicles, the resulting microdevice is capable for sensitive and accurate detection of cancer from ultra-small volumes of patient’s plasma samples.

Journal Cover

Effects of poly(ethylene glycol) on the wetting behavior and director configuration of lyotropic chromonic liquid crystals confined in cylinders

We investigate the effects of poly(ethylene glycol) (PEG) doping on nematic lyotropic chromonic liquid crystals (LCLCs) confined in a cylindrical cavity. We also confirm that the grafting of PEG to bare glass surfaces changes them from nemato-philic to nemato-phobic. Additionally, we observe that PEG-doped nematic SSY retains the double-twist director configuration as in the PEG-free case. However, the PEG-doped nematic SSY is accompanied by unprecedented domain-wall-like defects and heterogeneity in the director configuration. We propose multiple hypotheses on how PEG changes the director configuration, including the formation of meta-stable director configurations.

Circulating tumor cells (CTCs) in the blood have been used as diagnostic markers in patients with colorectal cancer (CRC). In this study, we evaluated a CTC detection system based on cell size to assess CTCs and their potential as early diagnostic and prognostic biomarkers for CRC


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