[48] Anal. Chem., 86(22) 11349-11356, (2014)

In this paper, we propose a centrifugal-force-based size-selective CTC isolation platform that can isolate and enumerate CTCs from whole blood within 30 s with high purity. Overall, our CTC isolation device enables rapid and label-free isolation of CTCs with high purity, which should greatly improve downstream molecular analyses of captured CTCs.

[47] ACS Appl. Mater. Interfaces., 6, 12189−12195 (2014)

This paper demonstrates  the first semiconductor-based nanofiber sensor suspended on carbon electrodes that has achieved by a relatively simple and cost-effective electrospinning method. Furthermore, these sensors demonstrate a high sensitivity, as well as a stable ohmic contact, due to the large surface area of the TiO2 NWs and the carbon-carbon contact between the suspended TiO2/C NFs and carbon electrodes. 


[46] Anal. Chem., 86 (8) 3841–3848 (2014)

This paper demonstrates that molecular detection of food-borne pathogens can be integrated into a single, compact device with great potential as a point of care diagnostic tool. Three main functions, DNA extraction, isothermal recombinase polymerase amplification (RPA), and detection, are integrated on a single device for the molecular detection of Salmonella.


[45] Integr. Biol., 6, 267-276 (2014)

Roles of small GTPases in lysophosphatidic acid-induced chemotaxis of SKOV3 ovarian cancer cells were first investigated using a novel microfluidic assay platform. Real-time tracking of individual cells in the rapid-prototyped multilevel microfluidic devices provided us substantial quantitative information about the chemotaxis of the cells under a linear and stable concentration gradient. This integrative study of cellular chemotaxis would provide us new biological insights, which could not be obtained through the traditional tools for cell migration assays.


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